Participants Needed for Mesothelioma Clinical Trial Vaccine Treatment

As cancer research scientists continue to explore vaccines as a way to treat cancer, we will continue to inform you about new experimental mesothelioma vaccine clinical trials recruiting volunteers. The mesothelioma clinical trial we report on here is intriguing because it is a pilot study. That means it is so experimental that it is a small preliminary study to help researchers get enough information to design a full-scale research project. Because it is a pilot study, it is being conducted by the National Cancer Institute only at the National Institutes of Health’s Clinical Center in Bethesda, Maryland which is a suburb of Washington D.C. So if you like the idea of going to Washington once a month for six months, then every three months for the next two years and then every six months for three years after that, this might be a clinical trial you might consider. But check with your oncologist first.

Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas Identifier NCT01143545

First received June 11, 2010

Last Updated May 3, 2014

Sponsor National Cancer Institute

Purpose Certain types of lung, esophageal, or thymic cancers and mesotheliomas have specific antigens (protein molecules) on their surfaces. Research studies have shown that giving a vaccine that contains antigens similar to these may cause an immune response, which may keep tumors from growing. Researchers are also interested in determining whether the chemotherapy drug cyclophosphamide and the anti-inflammatory drug celecoxib may help the vaccine work better.

Discussion of Outcome Measures Evaluate the safety and effectiveness of tumor cell vaccines in combination with cyclophosphamide and celecoxib in patients with cancers involving the chest.

Estimated Enrollment 25

Study Start Date May 2010

Estimated Study Completion Date May 2017

Eligibility Life expectancy of more than 12months, evidence of adequate bone marrow reserve, no hypertension or heart disease. For complete list, see study webpage.

Contacts and Locations


National Institutes of Health Clinical Center

9000 Rockville Pike

Bethesda, MD 20892

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Amir Hussain

Amir Hussain is the founder of Freemium World, a geek by nature and a professional Blog writer . I love to write about new technology trends, social media, hacking, blogging and much more.

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